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You should tell your doctor if any of the following side effects become severe or don't go away: Nausea, vomiting, diarrhea, or constipation. Stomach pain or cramping. Loss of appetite. Headache. Dizziness. Nervousness, irritability, or anxiety. Tearfulness. Increased or decreased energy.
Differences between Naloxone, Naltrexone and Vivitrol: Naloxone (Narcan) is a short acting drug which will bring a patient out of an opiate overdose by stripping the opiate from the opiate receptor and is a life saving drug. Naltrexone, a short acting opiate/alcohol blocking agent has been used for the last 30 years.
A dose of 50 mg once daily is recommended for most patients. The placebo-controlled studies that demonstrated the efficacy of Naltrexone hydrochloride tablets as an adjunctive treatment of alcoholism used a dose regimen of Naltrexone hydrochloride tablets 50 mg once daily for up to 12 weeks.
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The mean elimination half-life (T-?) values for naltrexone and 6-?-naltrexol are 4 hours and 13 hours, respectively. Naltrexone and 6-?-naltrexol are dose proportional in terms of AUC and Cmax over the range of 50 to 200 mg and do not accumulate after 100 mg daily doses.
What will happen if a patient drinks alcohol while taking naltrexone? Naltrexone does not reduce the effects of alcohol that impair coordination and judgment. Naltrexone may reduce the feeling of intoxication and the desire to drink more, but it will not cause a severe physical response to drinking. 5.
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