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BACTRIM (sulfamethoxazole and trimethoprim) is a synthetic antibacterial combination product available in DS (double strength) tablets, each containing 800 mg sulfamethoxazole and 160 mg trimethoprim; in tablets, each containing 400 mg sulfamethoxazole and 80 mg trimethoprim for oral administration.
Bactrim has an elimination half life of 6 to 12 hours. It usually takes around 5 to 6 half lives for a drug to be completely eliminated from your system. Other factors also affect elimination (age, health, weight, metabolism) but you can expect that your husband should be free of bactrim after about three days
Sulfamethoxazole in BACTRIM belongs to a group of medicines known as sulfonamides. Trimethoprim belongs to a group of medicines known as the benzylpyrimidines. BACTRIM works by stopping the growth of the bacteria causing the infection. BACTRIM does not work against infections caused by viruses, such as colds and flu.
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The mean serum half-lives of sulfamethoxazole and trimethoprim are 10 and 8 to 10 hours, respectively. However, patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment (see DOSAGE AND ADMINISTRATION section).
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