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Directions: Take Hydrea exactly as prescribed by your doctor. A typical dose for adults is 80 mg per kilogram of body weight taken in one dose every third day. If radiation is also being used, hydoxyurea dosing should start at least 7 days before the start of radiation and continue throughout and after treatment. Take this medication by mouth with or without food. Swallow the capsules whole. Take each dose with a full glass of water.
Possible side effect: Get emergency medical help if you have diarrhea, constipation, drowsiness, loss of appetite, nausea, vomiting, redness of skin, temporary hair loss, confusion, difficulty urinating, dizziness, headache, joint pain, sores in mouth or on lips, black or bloody stools, difficulty breathing, fever, chills, hallucinations, seizures, unusual bleeding. If you notice other effects not listed above, contact your doctor.
Hydroxyurea is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. Hydroxyurea is classified as an "antimetabolite."
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General information: Hydrea belongs to the group of medications known as antineoplastics. It affects certain cells in the body, such as cancer cells or sickled red blood cells. This medication is used in people with sickle cell anemia to reduce the number of painful crises caused by the disease and to reduce the need for blood transfusions. It is also used to treat several types of cancer (melanoma, chronic myelogenous leukemia, squamous cell carcinomas).
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